_Toxic Heavy Metals and Inflammatory Pathways_
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by Lyn Hanshew, M.D.
Inflammation is a symptom of heavy metal toxicity and is integral in the
development of illnesses such as hypertension, arteriosclerosis, asthma,
psoriasis, arthritis, hepatitis, acne, colitis, and many other degenerative
diseases. Inflammation can be caused by toxic heavy metals interfering with
the equilibrium of omega-3 and omega-6 fatty acids conversion pathways. The
specific biological functions of fatty acids depend upon the number and
position of double bonds and the length of the acyl chain.
Omega-3 fatty acids are a family of unsaturated fatty acids that are
important components of cell membranes. Alpha-Linolenic acid (ALA) is the only
essential omega-3, meaning that the body cannot produce ALA. It must be
obtained from dietary sources such as salmon, soy beans, flax seed oil,
walnuts and dark leafy vegetables. ALA is crucial for maintaining cardiovascular
health and can reduce the risk of diabetes and cancer through the
anti-inflammatory series-3 prostaglandin pathways.
ACZ nano® adsorbs molecules of certain sizes while rejecting larger ones.
Species with a kinetic diameter too large to pass through a Zeolite pore
are effectively "sieved."
ALA is converted to Eicosapentaenoic acid (EPA) though a series of three
enzymatic steps, dependent upon Vitamin B6, Magnesium, Zinc, Niacin and
Vitamin C. EPA is obtained from fish and fish oils and supports cardiovascular
health. EPA can be converted to biochemical intermediates involved in the
anti-inflammatory series-3 prostaglandins. Docosapentaenoic acid (DPA) and
Decosahexanenoic acid (DHA) can be made from EPA. DHA is also obtained from
fish, fish oils, human milk, egg yolks, liver, brain and other organ meats.
EPA and DHA are precursors to several classes of eicosanoids (mainly
inflammatory) and docosanoids (anti-inflammatory) that have important roles.
DHA is the most abundant omega-3 fatty acid in most tissues and is present in
large amounts in the brain and retina. DHA is required for infant brain
development and function, central nervous system development and optimal
visual acuity.
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eavy_metals_and_inflammatory_pathways.php)
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