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Tuesday, February 21, 2012

[AlternativeAnswers] Anti-Aging Supplements: Vitamin E: One Main Mission

 

Good Morning!

Anti-Aging Supplements: Vitamin E: One Main Mission

Vitamin E (tocopherols) are the most abundant fat-soluble antioxidant in the
body. One of the most efficient chain-breaking antioxidants available, Vitamin E
primarily defends against oxidation and lipid peroxidation, which is the
creation of unstable molecules containing more oxygen than is usual. Research
has demonstrated the broad role of vitamin E in promoting health. Vitamin E may
affect aging, [12] infertility, [13] heart disease, [15] Alzheimer�s, [14] and
diabetes. [12].

Vitamin E works together with other antioxidants, such as vitamin C, to offer
protection from some chronic diseases. Evidence exists that vitamin E can help
prevent atherosclerosis by interfering with the oxidation of low-density
lipoproteins (LDL), a factor associated with increased risk of heart disease.

In 1993, The New England Journal of Medicine published two reports, which found
that people who took vitamin E supplements had fewer deaths from heart disease.
[16].

Another component of Vitamin E is tocotrienols. Tocotrienols are potent
antioxidants which work against the damaging of fats by oxidation. [29,30].
Human studies have shown that, in addition to their antioxidant activity,
tocotrienols have other important functions, especially in maintaining a healthy
cardiovascular system. [31]. Test tube and animal studies indicate a possible
role for tocotrienols in protecting against breast cancer and skin cancer.

Like vitamin E, tocotrienols may offer protection against atherosclerosis by
preventing oxidative damage to LDL cholesterol. LDL cholesterol oxidation is
believed to be one of the triggering factors for atherosclerosis. [32]. Vitamin
E is found in vegetable oils, salad dressings, margarine, wheat germ,
whole-grain products, sunflower seeds, cashew nuts, spinach, green peas, sweet
potatoes, bean sprouts blackeyed peas, almonds and peanut butter. Recommended
doses of Vitamin E tochopheryl are 400 IU before age 40 and 800IU from age 40
onward.

Andrew Pacholyk, MS. L.Ac
http://www.peacefulmind.com/anti-aging.htm
Therapies for healing
mind, body, sp;irit

References

12. Devaraj, S., Jialal, I. Alpha tocopherol supplementation
decreases serum C-reactive protein and monocyte interleukin-6 levels
in normal volunteers and type 2 diabetic patients. Free Radical
Biology Med. 2000 Oct 15; 29(8): 790 2.

13. Devaraj, S., Jialal, I. Alpha tocopherol supplementation
decreases serum C-reactive protein and monocyte interleukin-6 levels
in normal volunteers and type 2 diabetic patients. Free Radical
Biology Med. 2000 Oct 15; 29(8): 790 2.

14. Dr. Marianne J. Engelhart of the Erasmus Medical Center in
Rotterdam, the Netherlands: Those with the highest intake of vitamin
C and vitamin E from food appeared to be the least likely to develop
Alzheimer's disease. The Journal of the American Medical Association.
6/26/03

15. Meydani M. Vitamin E and prevention of heart disease in high-risk
patients. Nutr Rev 2000;58:278-81.

16. 1993, The New England Journal of Medicine published two
epidemiologic studies which found that people who took vitamin E
supplements had fewer deaths from heart disease.

17. Heinonen OP, Albanes D, Virtamo J, Taylor PR, Huttunen JK,
Hartman AM, Haapakoski J, Malila N, Rautalahti M, Ripatti S, Maenpaa
H, Teerenhovi L, Koss L, Virolainen M, Edwards BK. Prostate cancer
and supplementation with alpha-tocopherol and beta-carotene:
incidence and mortality in a controlled trial. Department of Public
Health, University of Helsinki, Finland. Journal National Cancer
Institute. 1998 Mar 18;90(6):440-6, 441-7.

18. Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA,
Willerr WC. Intake of carotenoids and retinol in relation to risk of
prostate cancer. J Natl Cancer Inst 87:1767-1776, 1995

19. Dorgan JF, Sowell A, Swanson CA, Potischman N, Miller R.
Schussler N, Stephenson HEJr. Relationships of serum carotenoids,
retinol, a-tocopherol and selenium with breast cancer risk: results
from a prospective study in Columbia, Missouri (United States).
Cancer Causes Control 9:89-97, 1998

20. Antioxidants and age-related macular degeneration. Age-Related
Macular Degeneration Study Group. Journal of the American Optometric
Association. January 1996--Vol 67, No. 1.

21. Farr SA, Poon HF, Dogrukol-Ak D, Drake J, Banks WA, Eyerman E,
Butterfield DA, Morley JE. "The antioxidants alpha-lipoic acid and N-
acetylcysteine reverse memory impairment and brain oxidative stress
in aged SAMP8 mice." Geriatric Research Education and Clinical Center
(GRECC), VA Medical Center (151/JC), 915 N. Grand Boulevard, St.
Louis, MO 63109, USA.

22. Moini H, Packer L, Saris NE. Antioxidant and pro-oxidant
activities of alpha-lipoic acid and dihydrolipoic acid. Toxicol Appl
Pharmacol 2002 Jul 182:84-90

23. Lopez-Burillo S, Tan DX, Mayo JC, Sainz RM, Manchester LC, Reiter
RJ. Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic
acid differentially reduce oxidative DNA damage induced by Fenton reagents: a
study of their individual and synergistic
actions. Department of Biochemistry, Molecular Biology and
Physiology, School of Medicine, University of Valladolid, Valladolid,
Spain. 2001

24. Gregory JF, 3rd. Ascorbic acid bioavailability in foods and
supplements. Nutr Rev. 1993;51(10):301-303.

25. DeRitter E. Physiologic availability of dehydro-L-ascorbic acid
and palmitoyl-L-ascorbic acid. Science. 1951;113:628-631.

26. Johnston CS, Luo B. Comparison of the absorption and excretion of
three commercially available sources of vitamin C. J Am Diet Assoc.
1994;94(7):779-781.

27. Padayatty SJ, Levine M. Reevaluation of ascorbate in cancer
treatment: emerging evidence, open minds and serendipity. Journal
American College Nutrition. 2000;19(4):423-425.

28. Boylan MT, Crockard AD, Duddy ME, Armstrong MA, McMillan SA,
Hawkins SA. Interferon-beta 1a administration results in a transient
increase of serum amyloid A protein and C-reactive protein:
comparison with other markers of inflammation. Immunology Letters
2001; 75: 191-197.
29. Kamal-Eldin A, Appelqvist LA. The chemistry and antioxidant
properties of tocopherols and tocotrienols. Lipids 1996;31:671�701
[review].

30. Kamat JP, Devasagayam TPA. Tocotrienols from palm oil as potent
inhibitors of lipid peroxidation and protein oxidation in rat brain
mitochondria. Neurosci Lett 1995;195:179�82.

31. Theriault A, Chao JT, Wang Q, et al. Tocotrienol: a review of its
therapeutic potential. Clin Biochem 1999;32:309�19 [review].

32. Suarna C, Hood RL, Dean RT, Stocker R. Comparative antioxidant
activity of tocotrienols and other natural lipid-soluble antioxidants
in a homogeneous system, and in rat and human lipoproteins. Biochim
Biophys Acta 1993;1166:163�70.

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