Pantethine vs. Pantothenic Acid
Pantothenic Acid is the beta alanine amide of pantoic acid. A growth substance widely distributed in plant and animal tissues, and essential for growth of a number of organisms; dietary deficiency causes dermatitis in chicks, and dermatitis and achromotrichia in rats; Pantothenic Acid is a precursor to coenzyme A.
Pantethine is a dietary supplement that is related to vitamin B5 (pantothenic acid). Pantethine is used for lowering cholesterol, preventing inflammation, boosting the activity of the immune system, treating an inherited condition called cystinosis, treating gastrointestinal (GI) diseases, and improving athletic performance. It is also used for improving energy, lowering the risk of heart attack and stroke, improving adrenal function, protecting against mental and physical stress, and preventing allergy symptoms in people who are allergic to formaldehyde.
The advantage of taking Pantethine vs. Pantothenic Acid is one primary difference and that is in the effect between pantethine and pantothenic acid. Clinically, it is with regard to lipid lowering activity. Pantethine has been shown to have several lipid lowering effects while pantothenic acid does not appear to have these effects.
Pantethine in a dose of 300 mg three times daily has been shown to significantly reduce serum triglycerides, total cholesterol, and LDL cholesterol while raising HDL cholesterol.
Pantethine was especially effective in one study of diabetic patients on dialysis. These patients had a reduction in total cholesterol, VLDL, and triglycerides, although no change was noted in their HDL cholesterol. (Murray 1996)
Andrew Pacholyk MS L.Ac
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